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Case of the Week 427



What is the most likely diagnosis?

  • 42 year-old found unresponsive in morning



Two images from Unenhanced CT of Brain

  1. Cerebral aneurysm
  2. Bilateral subdural hematomas
  3. Transtentorial herniation
  4. Diffuse Axonal Injury
  5. Carbon Monoxide Poisoning

Additional Images - None

 

 

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Answer:

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5. Carbon Monoxide Poisoning

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More (Click Discussion Tab)


Carbon Monoxide Poisoning

General Considerations

  • Leading cause of accidental poisoning deaths in the United States
  • Most fatalities result from fires, malfunctioning stoves, exhaust systems, heaters, suicide attempts
  • Impairs oxygen delivery and has its most lethal effects on organs requiring high levels of oxygen, i.e. the brain and heart
  • Binds reversibly to hemoglobin much more avidly than oxygen (200-250 times more avidly) leading to high levels of carboxyhemoglobin
  • It also binds to myoglobin with an even greater affinity than to hemoglobin
  • Populations at risk for mortality are those over the age of 75, those with underlying cardiopulmonary disorders, neonates and the fetus in utero
  • Pathology in brain
  • White matter demyelination
  • Edema and necrosis bilaterally in the globus pallidus, caudate nucleus and cerebellum

MORE...


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This Week

42 year-old found unresponsive in morning
 
Presented as a series of cards, this podcast asks some of the most common causes of neuroimaging findings and diseases making it ideal for a quick review. Can be used as either an audio only or audio/video podcast.; Complements Video Flashcard Podcasts 15, 21,25, 38, 42, 46 and 47.
 
 
Some of the fundamentals of interpreting chest images
 
The top diagnostic imaging diagnoses that all medical students should recognize according to the Alliance of Medical Student Educators in Radiology
 
Recognizing normal and  key abnormal intestinal gas patterns, free air and abdominal calcifications
 
Recognizing the parameters that define a good chest x-ray; avoiding common pitfalls
 
How to recognize the most common arthritides


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LearningRadiology.com
is an award-winning educational website aimed primarily at medical students and radiology residents-in-training, containing  lectures, handouts, images, Cases of the Week, archives of cases, quizzes, flashcards of differential diagnoses and “most commons” lists, primarily in the areas of chest, GI, GU cardiac, bone and neuroradiology.